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The local inflammatory microenvironment in the ovary, characterized by elevated levels of pro-inflammatory cytokines such as IL-18 and IL-1, impairs the function of follicular granulosa cells and accelerates follicular atresia, ultimately contributing to polycystic-like morphological changes in the ovary (62)

These compounds are detected in blood before fasting and the degree of increase after 58 hr of fasting was moderate (2.03.4-fold increase

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[PMC free article] [PubMed] [Google Scholar] 194.Veronesi MC, Alhamami M, Miedema SB, Yun Y, Ruiz-Cardozo M, Vannier MW

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