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MitoSiege-driven catalase collapse: a GSH-responsive, mitochondria-targeted COF prodrug for amplified chemodynamic therapy

Cellular antioxidant systems, such as the thioredoxin (Trx) and glutathione (GSH) systems, function to reduce oxidative stress [11,12]

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To put it another way, Long COVID is associated with immune-inflammatory processes and decreased ANTIOX, while a subgroup of Long COVID patients additionally exhibits increased NO production, oxidative damage to proteins (PCs) and lipids with increased aldehyde formation (MDA), and an immune-oxidative stress response (increased MPO and CRP)

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