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Although vitamin B12 is considered extremely safe with excess amounts being excreted in the urine, please make sure the proper dosage and treatment schedule is used and determined by a veterinarian in relation to your dogs weight, medical condition, laboratory results and cause of the B12 deficiency

For Phase 1, that is 0.25mg

"National Diet and Nutrition Survey: Adults Aged 19 to 64 Years"

Adverse Event Reporting Severe Reactions Discontinue use and seek immediate medical attention if you experience severe or unusual side effects

Using RNase-free water when working with RNA prevents degradation and preserves the quality of the samples