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The phase II trial investigating the addition of the anti-HGF antibody rilotumumab to ECX (epirubicin, cisplatin and capecitabine) chemotherapy in gastric adenocarcinoma demonstrated a modest improvement in progression-free survival (PFS, 5.7 vs 4.2 months) and objective response rate (ORR, 39% vs 21%) [86] compared to placebo plus ECX

Antiapoptotic effects of EEBC in SCO-mediated memory deficit mice Accumulating evidence demonstrates that the cholinergic system is closely associated with the apoptotic pathway in neuronal cell death 28,29

Bile acids: Major regulator of the gut microbiome

Delta sleep-inducing peptide (DSIP)-like immunoreactivity in gut: coexistence with known peptide hormones