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Rosane Souza da Silva is a Research Awardee of the CNPq (Finance Code 307825/2022-1)

The stability of melphalan in the presence of chloride ion

Other contraindications and precautions for GLP-1 agonists include a history of severe allergic reactions to the medication or its components, acute or chronic pancreatitis, gallbladder disease or gallstones, and certain forms of diabetic retinopathy

After mutation of the PAZ RNA-binding pocket (F294A, Y311A), trigger variants with longer internal loops induced binding and polyubiquitylation no better than did the seed-only variant, supporting the idea that together, trigger-specific RNA trajectory and binding of the vacated PAZ pocket substantially contribute to ZSWIM8 selectivity for TDMD substrates

Priyanka, B., Patil, R