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Its a staple of cartoons and sitcoms alike: that telltale tic that signals a character is right on the very edge of sanity, so stressed out that their body is forced to betray them via a tiny but uncontrollable twitch of the eyelid

The long chain fatty acid buildup causes damage to the myelin sheath of the neurons of the brain, resulting in seizures and hyperactivity

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Neuropathol Appl Neurobiol (1999) 25(6):45967
