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IGF-1 has been advocated to induce tenogenic differentiation of stem cells
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Sunlight exposure and risk of lens opacities in a population-based study: the Salisbury Eye Evaluation project
however, it was not judged to be clinically relevant
PRDX3 and PRDX4 scavenge ROS within the mitochondria and ER, respectively, while PRDX5 and PRDX6 localize to multiple cellular compartments ( Additional detoxification systems include the thioredoxin (TRX1/2) pathway, which is particularly important for neutralizing ROS generated during disulfide bond formation in the ER, and superoxide dismutase 2 (SOD2), which catalyzes the conversion of superoxide into hydrogen peroxide (31, 32)
