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The medium in the basolateral chamber was collected at different time points and fluorescence signals were recorded using a microplate reader (FLUOstar Omega, BMG Labtech, Ortenberg, Germany) at excitation/emission wavelengths of 480 nm/530 nm, respectively

Intriguingly, under continuous drug treatment, a small fraction of DTPs can still re-enter the cell cycle and proliferate without detectable genomic mutations, which implies that DTPs possess strong survival ability [35, 36]

Its unique mechanism of promoting angiogenesis while simultaneously reducing inflammation has made it a subject of intense research interest for tissue repair and regeneration applications

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