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The key characteristics of neutrophils and their interactions with distinct cell types are discussed within the initial part of the review, whereas the second part focuses on their contributions to the pathophysiology of immune-driven diseases, including rheumatoid arthritis, atherosclerosis, inflammatory bowel disease, systemic lupus erythematosus, chronic obstructive pulmonary disease, and fibrotic disorders

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Furthermore, we used the LysoTracker probe to show that TFE3 -KO reduced the volume of the acidic compartment, including lysosomes (Supplementary Fig