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LiY.et al.2005The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy, 52

While the ER status has been used to identify breast cancer patients who may respond to TAM, there are still 30%50% of treated Er-positive breast cancer cells that show resistance to TAM ( A study involving the TAM-resistant cells named MCF-7 TR5 (TAM resistant to 5 M) reported that Z-ligustilide can enhance the inhibitory effect of TAM on the cell viability in MCF-7 TR5 and sensitized MCF-7 TR5 cells to TAM via promoting caspase-independent cell death ( TR5 ( Curcumin is a bioactive compound of the Chinese medicine turmeric that exhibits effective anti-cancer activity

Meanwhile, synthetic polymer materials, though tunable in mechanical performance and degradation via molecular design and composite engineering, suffer from poor cell recognition and limited bioactivity (Brinkmann et al., 2023

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