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Description
D., Sun, H
Despite its discovery in the early 1960s and its development for various indications, systematic clinical pharmacology explorations of NAC pharmacokinetics (PK), pharmacodynamic targets, drug interactions, and dose-ranging are sorely limited
In microorganisms, Escherichia coli's LRP (leucine-responsive regulatory protein) binds directly to lysine, regulating DAP operon transcription: when lysine is abundant, the LRP-lysine complex inhibits synthesis pathway genes
doi: 10.3109/10717544.2014.907372 231
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