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The perception of pain is not confined to a single pathway or brain region but arises from a complex pain matrix" that is shaped by emotions, beliefs, and expectations (referred to as the biopsychosocial model of pain), making the experience of pain unique to each individual

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However, start with one or the other to understand individual effects before adding complexity

10.1016/j.jmb.2010.12.039 52 NirgudeS.ChoudharyB
