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Perhaps most important among these are the Toll-like Receptors (TLR) including TLR-2 (348,349), TLR-4 (350), TLR-6 (351), TLR-7 (352), and TLR-9 (352)
Petersen, B
Winkler T
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Under stress, mitochondria release proinflammatory mediators, such as ATP, cardiolipin, ROS, and mtDNA, which, when released into the cytoplasm or extracellular space, can promote inflammation and trigger senescence or senescence-associated chronic diseases [208]
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