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In a human study, it was observed that long-term sleep deprivation decreased intracellular magnesium content and reduced exercise tolerance, which could subsequently be corrected through oral magnesium supplementation.98 Nielsen et al conducted a study investigating the role of magnesium supplementation in adult sleep disorders, and following 7 weeks of treatment with 320 mg/day of magnesium citrate, patients exhibited an overall improvement in their PSQI scores.9,99 Abbasi et al aimed to examine the effects of magnesium on insomnia in elderly individuals,10 and he administered 500 mg/day of magnesium to 46 elderly participants experiencing primary insomnia over an 8-week period, with outcomes including increased sleep duration and efficiency, as well as reduced ISI scores and sleep onset latency

10.2741/2175 Front

doi: 10.1016/j.redox.2017.01.021

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[PMC free article: PMC295551] [PubMed: 7860760] 849