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Najjar VA, Holt JRLE (1941) The excretion of specific fluorescent substances in the urine in pellagra

Pregnant or breastfeeding women, people with copper metabolism disorders like Wilsons disease, and anyone with active skin infections should speak with a doctor before starting

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If your energy or focus is lagging, a B12 boost is a quick, low-cost way to support your metabolism and nervous system

Fatigue is sometimes reported during the first two weeks at this dose, though it is difficult to determine whether this is a direct effect of the medication or a consequence of significantly reduced caloric intake