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Vitamin B12 deficiency can be due to a number of reasons

Cagnacci A, Zanin R, Napolitano A, Arangino S, Volpe A

The elevation of homocysteine is accentuated when the affected individual is low in folate or riboflavin, the latter serving as a cofactor for the MTHFR enzyme in the form of FAD

Biosynthesis and toxicological effects of patulin
