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Usually three treatments, spaced a week apart, are recommended for optimal tissue tightening that continues for several additional weeks

Although Drp1-Ser637 phosphorylation predominantly suppresses mitochondrial fission under most physiological conditions, emerging evidence indicates its biological functions exhibit cell type-specific dependency and are dynamically regulated by microenvironmental signaling cues and upstream regulatory networks (Serasinghe and Chipuk, 2017)

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It should not be injected into the densely innervated site (areas that have a large supply of nerves)