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Permeabilization and blocking was performed by adding PBS (Lonza) containing 0.1% saponin (Carl Roth) and 3% normal donkey serum (Abcam, Cambridge, UK) for 30 min at RT

As PD progresses, therapy becomes more complex, often requiring dose adjustments, polypharmacy, and the use of rescue treatments

Deteriorating muscle strength and function as we get older lead to debilitating conditions like frailty, which can be life threatening

Activation of nitric oxide synthase (iNOS) or (NOS 2 ) protein in macrophage stimulates the increased secretion of nitric oxide (NO) and NO-metabolite levels within the cell

Association pour la recherche sur le cancer (ARC)