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Common Symptoms of a Vitamin B12 Deficiency If you think you may be low, watch out for these symptoms: Feeling tired, fatigue and weakness Loss of appetite Constipation Weight loss Megaloblastic anemia Numbness and tingling Poor balance or coordination Confusion Memory loss Depression (21) Soreness of mouth and/or tongue (22) Be aware that many symptoms of B12 deficiency overlap with symptoms of other health conditions, so it's important to see your doctor for a definitive diagnosis

If B12 levels were low to begin with, longer-term benefits like red blood cell production or nervous system support may take several weeks

This timing can increase serum levels of beneficial compounds by as much as 50%

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