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Paul MS, Abhilash M, Varghese MV, Alex M, Harikumaran Nair R

It also has strong antioxidant effects, protects lipids and plasma lipoproteins, and acts as a protector of DNA and proteins against free radicals

To assess the effect of L-Cn on T cell subsets, PBMCs or purified T cells were stimulated with or without L-Cn (20 mg/mL) in the presence of anti-CD3/CD28 (5 g/mL) for 72 h and restimulated with or without L-Cn for another 6 h in the presence of PMA (50 ng/mL), ionomycin (0.75 g/mL), and BFA (1 g/mL)

The change in the DNA causes the enzyme to be more thermolabile, which means that the enzyme loses its activity when exposed to moderate heat

doi: 10.1152/jn.1998.79.4.1790 43 ShahrakiSEsmaeilpourKShabaniMSepehriGRajizadehMAManeshianMet al