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Description
10.1007/s11910-012-0294-3 38

Its level decreases with age (especially from the age of 45-50) and as the body's defence needs increase (immunity, liver detoxification, antioxidant defences...)

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Due to significant controversial findings in MTHFR mutation and DNA methylation in both healthy populations and psychiatric patients, investigation of MTHFR activity in peripheral samples might be important

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