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In cases of suspected cobalt hypersensitivity, an intradermal test dose should be administered

Trichoscopic observations Finding: At baseline, trichoscopy revealed classic signs of androgenetic alopecia in both groups: hair diameter diversity (hairs of very different thicknesses), perifollicular pigmentation (brown halos around follicles), and yellow dots (empty follicle openings filled with sebum)

These hypotheses have sprung from its perceived potential to stimulate the production of collagen, elastin, and glycosaminoglycans, crucial intercellular matrix components

Goldenberg N, Barkan A

doi: 10.1080/15438620701693249