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The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 325

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262-OR: Pemvidutide, a GLP-1/glucagon dual receptor agonist, in subjects with overweight or obesitya 48-week, placebo-controlled, phase 2 (MOMENTUM) trial

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In WT mice, although cagrilintide treatment led to significant weight loss, the changes in body composition compared to vehicle-treated mice did not reach statistical significance, with fat mass decreasing by 7% ( P = 0.2) and lean mass increasing by 5% ( P = 0.14