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doi: 10.1016/j.phymed.2021.153582
Chukyo A, Chiba T, Kambe T, Yamamoto K, Kawakami K, Taguchi K, et al

5 Mantle D, Hargreaves IP

Braun, Theodore P, et al

If it's past the recommended 2-4 week window, even if it looks fine, its potency is likely compromised, and it's best to start with a fresh vial
