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Glutathione synthesis in cancer cells is largely dependent on cysteine, a precursor derived from cysteine, which is transported into the cell via the xCT (SLC7A11) transporter 14

PRMT5 inhibitors GSK591 and ly-283 caused a broad inhibition of transcriptome splicing in GBM cells, particularly affecting the products of cell cycle genes and prolonged survival in the PDX mouse model

Antioxidative effects In cancer cells, overcoming oxidative stress is a critical step for tumor progression

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Epitalon acts antioxidatively and supports the protection of neurons against damage