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Neuron 111 , 142144 (2023)
From these results, it could be inferred that CaOx-induced ferroptosis, as observed in the previous series of biochemical reactions, reduced the ability of cells to resist oxidation, thereby resulting in Fe2+ overload, mitochondrial damage and an increase in lipid peroxidation, which then induced an intracellular ROS outbreak, eventually causing severe cell injury
gasseri identified as a key mediator
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Alveolar defects have also been linked to reduced functional gas exchange (34)
