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Colchicine, a natural product extracted from the bulb of autumn colchicum, has been successfully used in the treatment of inflammatory diseases for millennia

BMC Genetics

Mechanism of Action in Humans: While there is substantial preclinical evidence on the molecular mechanisms of bioactive compounds in periodontal tissues, these mechanisms have not been fully validated in human studies

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Jin Z, Mantri Y, Retout M, Cheng Y, Zhou J, Jorns A, Fajtova P, Yim W, Moore C, Xu M, Creyer MN, Borum RM, Zhou J, Wu Z, He T, Penny WF, ODonoghue AJ and Jokerst JV, Angew

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