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J Biol Chem 285:4152532

Building on this foundation, we highlight representative studies that integrate RT with cGAS-STING pathway activation, focusing on three key aspects: (1) enhancing tumor and immune cell responses, (2) remodeling the TME, and (3) multimodal therapies combining RT, STING agonists, and other therapeutic strategies

[31] identified lactylation at lysine residues 281 and 345 of methyltransferase 3 (METTL3) in HEK293T cells, enhancing its affinity for N6-methyladenine (m6A)-modified RNA