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This portion of BCKDH is present on the endoplasmic reticulum (ER) and interacts with AMP deaminase 3 (AMPD3), and is negatively regulated by AMPD3

99% purity is essential for all melanocortin receptor pharmacology studies, comparative SAR research, pro-sexual behaviour paradigms, and melanogenesis biology , where impurities including the linear uncyclised peptide, partially oxidised species, or C-terminal amide hydrolysis product (PT-141) would show altered receptor subtype selectivity and confound mechanistic attribution