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For instance, PM2.5, which induces oxidative stress by generating ROS, may cause endothelial dysfunction, which affects the cochlear blood supply and increases the risk of hearing loss (188)

For example, one animal study led researchers to conclude that the gastroprotective benefits of BPC-157 are dependent on the route of administration

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The framework provides the scientific community with a steppingstone for further discussion and refinement

The interplay between NOX, mutant SOD1, and microglia in the production of superoxide is therefore potentially important, and more studies in this area are warranted (Valdmanis et al., 2008