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Description
Zinc is an essential trace element that plays a critical role in gene regulation, enzymatic function, and the integrity of protein structures (Qu et al., 2023[352])
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A., Matherly L
Thus, pyruvate-induced competitive inhibition of -ketoglutarate will only contribute to the stability of HIF-1 but not to the functional activity of HIF-1 in non-hypoxic cells
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