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Additionally, navitoclax is almost impenetrable to the blood brain barrier, thus, the current drugs are not able to reach the brain parenchyma (67)

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Lyophilized (Powder) Storage Before reconstitution: Store in freezer (-20C) for long-term storage (up to 2 years) Refrigerator storage (2-8C) acceptable for shorter periods (up to 6 months) Keep away from light and heat Original sealed vial is best Reconstituted Solution Storage After mixing with bacteriostatic water: Always refrigerate at 2-8C (36-46F) Use within 30 days for optimal potency Protect from light (use amber vials or wrap in foil) Never freeze reconstituted peptides Gently swirl (don't shake) before drawing doses Handling Best Practices To preserve peptide integrity: Reconstitution technique : Add bacteriostatic water slowly down the side of the vial, not directly onto the powder Gentle mixing : Swirl gently