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Description
The feedback regulation of PGC-1 by Fundc1 deficiency was also observed in primary cardiomyocytes, and the increased mRNA levels of PGC-1, NRF1, and TFAM in CK2-deleted cells were diminished when FUNDC1 was knocked down, suggesting that mitobiogenesis and mitochondrial turnover are accelerated by FUNDC1-mediated mitophagy [236]

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BPC-157 is a specialized tool for one job (healing), while GLP-1s are precision instruments designed for another (metabolic regulation and weight loss)

36:e101143
The challenge with ankle healing relates partly to the structures involved
