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In vivo and in vitro models were used to separate direct islet effects from systemic influences of Taz deficiency

Origin and Development While sometimes described as being "derived from a protein in stomach acid"[4], the precise origin of BPC-157 requires clarification: It was initially claimed to be isolated from human gastric juice[1] Some researchers have questioned whether the claim that it was derived from a stomach protein is well-substantiated[5] Also known by alternative designations including BPC-15, PL-10, PLD-116, and PL14736[1] The peptide's name"Body Protection Compound"reflects its observed protective effects on various tissues, while "157" refers to its specific sequence position in the putative parent protein[4]

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As a major cause of morbidity and mortality globally, hypertension remains a serious threat to global public health