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ML226 also stabilized HIF-1 in a nonprolyl-hydroxylated form (Extended Data Fig

Interventions included coordinating with neurologists for medication refills and consultations, adjusting appointment dates, and referring patients to hospitals if motor symptoms worsened

The variants that cause G6PD deficiency are grouped into classes correlating with disease severity, with class I being most severe and class IV indicating no disease

Indeed, transcriptomic data from multiple studies showed that fat-7 is consistently downregulated in nuo-6 and isp-1 mutants (Park et al, 2020

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