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The first clear evidence that gastric surgery can accelerate alcohol absorption came in 2002, when Klockhoff and collaborators found that RYGB caused women to reach ~ 28% higher peak BACswithin 5 minutes, compared to 25 minutes in non-operated women matched for age and BMI (245)

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Some authors question the real existence of SE, claiming the presence of apparent SE: a normal-length esophagus that is folded into the chest and appears to be short before extensive mediastinal mobilization [53]

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It works through nitric oxide modulation, VEGF-driven angiogenesis, and the FAK-paxillin cell migration pathway

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These may be followed by ultrastructural changes consistent with irreversible cell injury, including actual disruption of mitochondria, release of lysosomal enzymes, and rupture of cell membranes

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Serious side effects are rare

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