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A recent systematic review [81] on RCTs investigating high-dose melatonin ( 10 mg) in adults over 30 years of age was included

However, mGluR5 was highly expressed in the forebrain and limbic structures [28]

Costa A, Scholer-Dahirel A, Mechta-Grigoriou F

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B., Mechanistic Studies on Cancer Cell Interaction and its Chemosensitization Effect, Frontiers in Pharmacology 8 (2017): 105
