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Similarly, SF has been suggested as a potential candidate for adjuvant therapy against cerebral ischemiareperfusion injury, and experimental results showed SF to improve outcomes and slow cerebral ischemic/reperfusion injury via inhibition of NLRP3 inflammasomes and reduced MPO levels, reflecting neutrophil infiltration in the ischemic cerebral cortex [144,145]

One possibility could be that the bacterium exerts direct effects, which would imply that the bacterium can colonize organs other than the stomach

Mortensen et al., 2010a)

Ethics declarations Competing interests G.C.F

Particulate contamination and stability of three additives in 0.9% sodium chloride injection in plastic and glass large-volume containers