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States With Limited Type 2 Diabetes GLP-1 Coverage A smaller subset of the states mentioned above with no coverage for obesity-indicated GLP-1sincluding the District of Columbia, Florida, and New Jerseyalso limits coverage for Type 2 diabetes-indicated GLP-1s

Food and Drug Administration (FDA) for the diagnosis, treatment, cure, or prevention of any disease or medical condition

If pregnancy is planned, the medication should be discontinued at least two months before attempting conception due to the long washout period of semaglutide

The MOTS-c side effects profile is relatively mild, though the peptide faces bioavailability and stability challenges that limit its clinical development

Rapid development of tolerance to the behavioral actions of cholecystokinin