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7% of infants weighing less than 1500 g are affected by NEC 3 with mortality rate as high as 30% 4

In our recent work aiming to study the glutathione redox state in end-stage renal disease patients we observed a doubling of GSSG levels in RBCs of these patients as compared with age-matched healthy control subjects [49]

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[PubMed] [Google Scholar] Schubert F., Khn S., Gallinat J., Mekle R., Ittermann B

LSH, a DNA methylation modifier and a reader of 5-hmC, increases the 5-hmC levels at the promoters of the lipid metabolism-associated gene GLUT1 (glucose transporter type 1) and fatty acid desaturase genes SCD1 (stearoyl-CoA desaturase 1) and FADS2 (fatty acid desaturase 2) to activate their expression in H358 cells and PC9 cells[115, 116]