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As rats on the fcHF diet lacked the sugar component and consumed more calories from fat compared to rats on the fcHFHS diet, and fat intake was the most inhibited after MTII administration, these data point toward an important role for diet composition and particularly the fat content in the diet in sensitivity to melanocortins

Soluble cell lysates containing [ 3 H] inositol phosphate were transferred onto Dowex AGX8 chromatography columns to separate total IP by anion exchange chromatography

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It has catabolic effects on energy stores such as adipose tissue and muscle, with the goal of mobilizing glucose into the blood to sustain the brain in the fight-or-flight response

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