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394,395,396,397,398,399,400 In aggregate, the pro-angiogenic mechanism in melanoma is of rather complexity and highly interconnected due to the co-existence of multiple stimulatory ligands and receptors that exert their function through both paracrine and autocrine manners, which might be the reason for the limited therapeutic efficacy of treatment with a monoclonal antibody neutralizing VEGF-A in melanoma

Aysha Jebin and Suresh, 2023
Nature 485, 661665

Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases
Epub 2018 Jan 6
