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Current literature suggests that the L-carnitine system is perturbed in AD, with multiple studies showing that proteins and metabolites related to the L-carnitine system are altered in the brain, CSF, and plasma of AD patients (Makar et al., 1995

weight loss started from week 4, progressed steadily, and reached a nadir at week 60, showing progressive reduction over time, though specific intermediate monthly averages (e.g., at 3, 6, or 12 months) are not detailed in the main trial publication

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doi: 10.1016/S1570-0232(02)00617-7

These symptoms can escalate to life-threatening difficulties for individuals with comorbidities such as type II diabetes, frailty, heart disease and general aging