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Live-cell imaging and analysis Primary neurons or tissue samples were cultured on -Dish 35 mm (ibidi 80136) or -Dish 35 mm with location grids (ibidi 80156) for 610 DIV at 37 C and 5% CO 2

Indeed, in both studies, the highest frequency of TEAEs was in the normal function groups, possibly owing to the smaller sample sizes in the more severe impairment groups, or alternatively because participants with more serious health concerns, such as those with severe renal or hepatic impairment, may be less likely to notice or report mild or moderate TEAEs, as observed in populations with cancer [21]

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