glutathione is synthesized from magnesium in Our Diet and Its Role in the Body: Disease Prevention to Anti-Aging Glutathione Synthetase - an overview
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References Zhao J, Zhang X, Guan T, Wang X, Zhang H, Zeng X, et al

(3,4, 5) Supporting the Immune System
Kisich KO, Gelperina S, Higgins MP, Wilson S, Shipulo E, Oganesyan E, et al

Maintain a Healthy Weight Excess weight increases the risk of fatty liver disease

Therefore, if a patient is on a lower dose of metformin, they may not need to take additional vitamin B-12 supplementation
