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diarrhea could lead to dehydration if it is severe
doi:10.1111/j.1365-313X.2007.03280.x
Psychopharmacology, 185 (1), 93-103
Internalization has also been widely considered as the first step in receptor recovery from desensitization, leading to re-insertion of nondesensitized/reactivated receptors in the plasma membrane
The only downside was that the process took longer than I expected on my first try because I was being extra careful
