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This FOXO4-p53 interaction occurs within nuclear PML (promyelocytic leukemia) bodies and is critical for maintaining the viability of senescent cells without it, p53 is free to translocate to mitochondria and trigger intrinsic apoptosis

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10.1111/bjd.16106 [DOI] [PubMed] [Google Scholar] 75.Wilsmann-Theis D, Frambach Y, Philipp S, Weyergraf AJ, Jacobi A, Mssner R, et al

True positivity was confirmed in 16 samples, according to a greater than 30% difference in absorbance (specificity cut-off value) compared to the GX-G3-spiked samples

doi: 10.1038/nchembio.2239 [DOI] [PMC free article] [PubMed] [Google Scholar] 45.Auberger P, Favreau C, Savy C, Jacquel A, Robert G
