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Dogs that are not receiving a balanced diet rich in B12, which is found in animal-based products like meat, fish, and eggs, may develop a deficiency

For vitamin B12, this relatively modest daily requirement reflects the body's efficient recycling mechanisms and the vitamin's storage capacity in the liver, which can maintain reserves for several years (typically 2-5 mg)

These findings suggest that NNMT inhibition may influence tumor cell line phenotypes in vitro through both metabolic and epigenetic mechanisms, making 5-amino-1MQ a valuable tool for investigating the metabolic characteristics of different tumor cell lines

12 GhemrawiR.PooyaS.LorentzS.GauchotteG.ArnoldC.GueantJ.-L.et al (2013)