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Searle E, Quach H, Wong SW, et al

To recap: You are most likely to benefit from phentermine if you Have never used phentermine before Do NOT have a history of yo-yo dieting Are younger (less than 50) Are ALSO eating healthy Are ALSO sleeping well at night Are ALSO avoiding/reducing stress Are ALSO exercising (but not over-exercising) Do NOT have thyroid disease, leptin resistance, or insulin resistance If you dont fit into the categories listed above it doesnt mean that phentermine wont work for you, but it does mean that it probably wont be as effective as other therapies

In preclinical models, NNMT inhibition has been shown to mimic and boost exercise-mediated improvements in muscle function, even in sedentary subjects

Holistic recommendations for diet, exercise, and lifestyle modifications

Canadian Medical Association Journal 1999;161:1469