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Feb 2010;133(2):136-43

Intelligent triggering of nanomicelles based on a ROS-activated anticancer prodrug and photodynamic therapy (PDT)-synergistic therapy for lung cancers

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Compared to Supersomes, human S9 and hepatocyte-based assays showed slightly improved metabolite coverage with human liver microsomes providing the closest representation of human in vivo amide hydrolysis (differing from in vivo metabolism in the cases of acetanilide, paracetamol and lidocaine)

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